| ncRNA name | PKC δ siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Mus musculus |
| Tissues/Cell_line | retinas |
| Methods | Western blot, siRNA injection, RT-PCR, immunohistochemistry |
| Expression pattern | associated |
| Functional description | In diabetic retina and advanced glycation end product-treated human retinal microvascular endothelial cells, vascular leakage and loss of ZO-1 and ZO-2 on retinal vessels were effectively restored or prevented with treatment of rottlerin, transfection of PKC-delta-DN, or siRNA for PKC delta. |
| PubMed ID | 20110406 |
| Year | 2010 |
| Title | Inhibition of protein kinase C delta attenuates blood-retinal barrier breakdown in diabetic retinopathy. |
| Drug-related ncRNA | NO |
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